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KMID : 0391520100180010112
Journal of the Korean Child Neurology Society
2010 Volume.18 No. 1 p.112 ~ p.116
A Case of Pediatric Nephrolithiasis Associated with Topiramate Treatment
Hong Kyung-Taek

Ryu Hye-Won
Doo Ki-Hyun
Cho Jae-So
Cho An-Na
Lim Byung-Chan
Chae Jong-Hee
Kim Ki-Joong
Hwang Yong-Seung
Hwang Hee
Abstract
Topiramate is an antiepileptic drug widely used to treat various seizures, mood disorders and migraine based on its various pharmacological mechanisms. Even though nephrolithiasis is listed as one of its side effects, there have been no cases reporting nephrolithiasis caused by use of topiramate on Korean pediatric patients. Since the use of topiramate is increasing in many patients, the possibility of nephrolithiasis after the treatment needs to be considered. Here, we report our experience in correcting neprholithiasis by simply discontinuing topiramate without administering any additional treatments.
KEYWORD
Topiramate, Nephrolithiasis, Antiepileptics, Side effects
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